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Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations

Glioblastoma resists chemoradiotherapy, then, recurs to be a fatal space-occupying lesion. The recurrence is caused by re-growing cell populations such as glioma stem cells (GSCs), suggesting that GSC populations should be targeted. This study addressed whether a novel anti-cancer drug, OTS964, an i...

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Detalles Bibliográficos
Autores principales: Sugimori, Michiya, Hayakawa, Yumiko, Koh, Masaki, Hayashi, Tomohide, Tamura, Ryoi, Kuroda, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790444/
https://www.ncbi.nlm.nih.gov/pubmed/29423027
http://dx.doi.org/10.18632/oncotarget.23077