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Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma

Accumulating evidence has proved that glioma stem-like cells (GSCs) are responsible for tumorigenesis, treatment resistance, and subsequent tumor recurrence in glioblastoma (GBM). In this study, we identified dual specificity protein kinase TTK (TTK) as the most up-regulated and differentially expre...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Xie, Yuchen, Bai, Xiaobin, Wang, Ning, Yu, Hai, Deng, Zhong, Lian, Minxue, Yu, Shuo, Liu, Hao, Xie, Wanfu, Wang, Maode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790447/
https://www.ncbi.nlm.nih.gov/pubmed/29423030
http://dx.doi.org/10.18632/oncotarget.23152