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Melatonin attenuated brain death tissue extract-induced cardiac damage by suppressing DAMP signaling

We tested the hypothesis that melatonin prevents brain death (BD) tissue extract (BDEX)-induced cardiac damage by suppressing inflammatory damage-associated molecular pattern (DAMP) signaling in rats. Six hours after BD induction, levels of a DAMP component (HMGB1) and inflammatory markers (TLR-2, T...

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Detalles Bibliográficos
Autores principales: Sung, Pei-Hsun, Lee, Fan-Yen, Lin, Ling-Chun, Chen, Kuan-Hung, Lin, Hung-Sheng, Shao, Pei-Lin, Li, Yi-Chen, Chen, Yi-Ling, Lin, Kun-Chen, Yuen, Chun-Man, Chang, Hsueh-Wen, Lee, Mel S., Yip, Hon-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790481/
https://www.ncbi.nlm.nih.gov/pubmed/29423064
http://dx.doi.org/10.18632/oncotarget.23180