Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance

Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological role of PRL-3 in B cell ALL (B-ALL). Here, we demonstrate that PRL-3 expression...

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Detalles Bibliográficos
Autores principales: Hjort, Magnus A., Abdollahi, Pegah, Vandsemb, Esten N., Fenstad, Mona H., Lund, Bendik, Slørdahl, Tobias S., Børset, Magne, Rø, Torstein B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790482/
https://www.ncbi.nlm.nih.gov/pubmed/29423065
http://dx.doi.org/10.18632/oncotarget.23186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790482/
https://www.ncbi.nlm.nih.gov/pubmed/29423065
http://dx.doi.org/10.18632/oncotarget.23186

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