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Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting

Tumor microenvironment (TME) is characterized by multiple immune suppressive mechanisms able to suppress anti-tumor effector cell immunity. Combinatorial strategies, including vaccine and immunomodulatory drugs, need to be developed for improved immunotherapy efficacy. A novel combinatorial approach...

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Detalles Bibliográficos
Autores principales: Petrizzo, Annacarmen, Mauriello, Angela, Luciano, Antonio, Rea, Domenica, Barbieri, Antonio, Arra, Claudio, Maiolino, Piera, Tornesello, Marialina, Gigantino, Vincenzo, Botti, Gerardo, Ciliberto, Gennaro, Buonaguro, Franco M., Tagliamonte, Maria, Buonaguro, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790484/
https://www.ncbi.nlm.nih.gov/pubmed/29423067
http://dx.doi.org/10.18632/oncotarget.23181