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Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting
Tumor microenvironment (TME) is characterized by multiple immune suppressive mechanisms able to suppress anti-tumor effector cell immunity. Combinatorial strategies, including vaccine and immunomodulatory drugs, need to be developed for improved immunotherapy efficacy. A novel combinatorial approach...
Autores principales: | Petrizzo, Annacarmen, Mauriello, Angela, Luciano, Antonio, Rea, Domenica, Barbieri, Antonio, Arra, Claudio, Maiolino, Piera, Tornesello, Marialina, Gigantino, Vincenzo, Botti, Gerardo, Ciliberto, Gennaro, Buonaguro, Franco M., Tagliamonte, Maria, Buonaguro, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790484/ https://www.ncbi.nlm.nih.gov/pubmed/29423067 http://dx.doi.org/10.18632/oncotarget.23181 |
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