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Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux

INTRODUCTION: Cholangiocarcinoma is characterized by aggressive tumor growth, high recurrence rates, and resistance against common chemotherapeutical regimes. The polyether-antibiotic Salinomycin is a promising drug in cancer therapy because of its ability to overcome apoptosis resistance of cancer...

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Detalles Bibliográficos
Autores principales: Klose, Johannes, Guerlevik, Engin, Trostel, Tina, Kühnel, Florian, Schmidt, Thomas, Schneider, Martin, Ulrich, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790487/
https://www.ncbi.nlm.nih.gov/pubmed/29423070
http://dx.doi.org/10.18632/oncotarget.23339