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The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

Cutaneous melanoma, which develops from the pigment producing cells called melanocytes, is the most deadly form of skin cancer. Unlike the majority of other cancers, the incidence rates of melanoma are still on the rise and the treatment options currently available are being hindered by resistance,...

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Detalles Bibliográficos
Autores principales: Hanson, Kimberley, Robinson, Stephen R., Al-Yousuf, Karamallah, Hendry, Adam E., Sexton, Darren W., Sherwood, Victoria, Wheeler, Grant N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790502/
https://www.ncbi.nlm.nih.gov/pubmed/29423085
http://dx.doi.org/10.18632/oncotarget.23378