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The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth
Cutaneous melanoma, which develops from the pigment producing cells called melanocytes, is the most deadly form of skin cancer. Unlike the majority of other cancers, the incidence rates of melanoma are still on the rise and the treatment options currently available are being hindered by resistance,...
Autores principales: | Hanson, Kimberley, Robinson, Stephen R., Al-Yousuf, Karamallah, Hendry, Adam E., Sexton, Darren W., Sherwood, Victoria, Wheeler, Grant N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790502/ https://www.ncbi.nlm.nih.gov/pubmed/29423085 http://dx.doi.org/10.18632/oncotarget.23378 |
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