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Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia

B-cell acute lymphoblastic leukemia (B-ALL) is a rare heterogeneous disease characterized by a block in lymphoid differentiation and a rapid clonal expansion of immature, non-functioning B cells. Adult B-ALL patients have a poor prognosis with less than 50% chance of survival after five years and a...

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Detalles Bibliográficos
Autores principales: Boullosa, Laurie Freire, Savaliya, Payalben, Bonney, Stephanie, Orchard, Laurence, Wickenden, Hannah, Lee, Cindy, Smits, Evelien, Banham, Alison H., Mills, Ken I., Orchard, Kim, Guinn, Barbara-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790505/
https://www.ncbi.nlm.nih.gov/pubmed/29423088
http://dx.doi.org/10.18632/oncotarget.23380