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Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts

PURPOSE: There is a need for adjuvant/neo-adjuvant treatment strategies to prevent metastatic relapse in soft tissue sarcoma (STS). Tumor hypoxia is associated with a high-risk of metastasis and is potentially targetable. This study aimed to derive and validate a hypoxia mRNA signature for STS for f...

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Detalles Bibliográficos
Autores principales: Yang, Lingjian, Forker, Laura, Irlam, Joely J., Pillay, Nischalan, Choudhury, Ananya, West, Catharine M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790513/
https://www.ncbi.nlm.nih.gov/pubmed/29423096
http://dx.doi.org/10.18632/oncotarget.23280