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A plasma telomeric cell-free DNA level in unaffected women with BRCA1 or/and BRCA2 mutations: a pilot study

Plasma cell-free DNA (cfDNA) is a small DNA fragment circulating in the bloodstream originating from both non-tumor- and tumor-derived cells. A previous study showed that a plasma telomeric cfDNA level decreases in sporadic breast cancer patients compared to controls. Tumor suppressor gene products...

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Detalles Bibliográficos
Autores principales: Dey, Shatovisha, Marino, Natascia, Bishop, Kanokwan, Dahlgren, Paige N., Shendre, Aditi, Storniolo, Anna Maria, He, Chunyan, Tanaka, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790533/
https://www.ncbi.nlm.nih.gov/pubmed/29423116
http://dx.doi.org/10.18632/oncotarget.23767