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Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

Reactive oxygen species (ROS) play important roles in fundamental cellular processes such as proliferation and survival. Here we investigated the effect of oxidative stress on stem cell maintenance and neuronal differentiation in a human embryonic stem cell (hESC) model, Ntera2 (NT2). CM-H2DCFDA and...

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Detalles Bibliográficos
Autores principales: Hu, Qidong, Khanna, Puja, Ee Wong, Belinda Shu, Lin Heng, Zealyn Shi, Subhramanyam, Charannya Sozheesvari, Thanga, Lal Zo, Sing Tan, Sharon Wui, Baeg, Gyeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790534/
https://www.ncbi.nlm.nih.gov/pubmed/29423117
http://dx.doi.org/10.18632/oncotarget.23786