Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism()

In the pharmaceutical industry, the analysis of atropisomers is of considerable interest from a scientific and regulatory perspective. The compound of interest contains two stereogenic axes due to the hindered rotation around the single bonds connecting the aryl groups, which results in four potenti...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Hu, Yue, Galella, Elizabeth, Tomasella, Frank P., Fish, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790684/
https://www.ncbi.nlm.nih.gov/pubmed/29404032
http://dx.doi.org/10.1016/j.jpha.2017.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790684/
https://www.ncbi.nlm.nih.gov/pubmed/29404032
http://dx.doi.org/10.1016/j.jpha.2017.03.003

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