A stability-indicating LC–MS/MS method for zidovudine: Identification, characterization and toxicity prediction of two major acid degradation products

Zidvovudine (AZT) is a nucleoside analogue reverse transcriptase inhibitor (NRTI), a class of anti-retroviral drug. A stability-indicating assay method for AZT was developed in line with ICH guideline. Successful separation of AZT and its degradation products was achieved by gradient elution mode on...

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Detalles Bibliográficos
Autores principales: Devrukhakar, Prashant S., Shiva Shankar, M., Shankar, G., Srinivas, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790685/
https://www.ncbi.nlm.nih.gov/pubmed/29404043
http://dx.doi.org/10.1016/j.jpha.2017.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790685/
https://www.ncbi.nlm.nih.gov/pubmed/29404043
http://dx.doi.org/10.1016/j.jpha.2017.01.006

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