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DNA-binding studies of valrubicin as a chemotherapy drug using spectroscopy and electrochemical techniques

In this study, the molecular interactions between valrubicin, an anticancer drug, and fish sperm DNA have been studied in phosphate buffer solution (pH 7.4) using UV–Vis spectrophotometry and cyclic voltammetry techniques. Valrubicin intercalated into double stranded DNA under a weak displacement re...

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Detalles Bibliográficos
Autores principales: Hajian, Reza, Hossaini, Parvin, Mehrayin, Zahra, Woi, Pei Meng, Shams, Nafiseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790692/
https://www.ncbi.nlm.nih.gov/pubmed/29404035
http://dx.doi.org/10.1016/j.jpha.2017.01.003