Separation and determination of acetyl-glutamine enantiomers by HPLC–MS and its application in pharmacokinetic study

A high-performance liquid chromatography coupled with mass spectrometry (HPLC–MS) method was established for the separation and determination of acetyl-glutamine enantiomers (acetyl-L-glutamine and acetyl-D-glutamine) simultaneously. Baseline separation was achieved on Chiralpak AD-H column (250 mm...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxiao, Gao, Lei, Zhang, Zunjian, Tian, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790696/
https://www.ncbi.nlm.nih.gov/pubmed/29404053
http://dx.doi.org/10.1016/j.jpha.2017.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790696/
https://www.ncbi.nlm.nih.gov/pubmed/29404053
http://dx.doi.org/10.1016/j.jpha.2017.06.003

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