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Identification and characterization of related substances in EVT-401 by hyphenated LC–MS techniques

A sensitive and selective method was developed for the separation and characterization of related substances (RSs) in EVT-401 by hyphenated LC–MS techniques. Complete separation of the RSs was achieved with an Inertsil ODS-SP column (250 mm×4.6 mm, 5 µm) by linear gradient elution using a mobile pha...

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Detalles Bibliográficos
Autores principales: Zhu, Binan, Lu, Yuting, Chen, Leilin, Yu, Binbin, Liu, Yuexin, Song, Min, Hang, Taijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790700/
https://www.ncbi.nlm.nih.gov/pubmed/29404042
http://dx.doi.org/10.1016/j.jpha.2017.03.008