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Chromatoprobe as a sample-sparing technique for residual solvent analysis of drug discovery candidates by gas chromatography
In drug discovery research, residual solvent measurement is an integral part of purity analysis for synthesis of a drug candidate before it is used for toxicity testing. This is usually carried out using gas chromatography (GC) with direct injection sample introduction. This method requires testing...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790705/ https://www.ncbi.nlm.nih.gov/pubmed/29404048 http://dx.doi.org/10.1016/j.jpha.2017.03.009 |