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Chromatoprobe as a sample-sparing technique for residual solvent analysis of drug discovery candidates by gas chromatography

In drug discovery research, residual solvent measurement is an integral part of purity analysis for synthesis of a drug candidate before it is used for toxicity testing. This is usually carried out using gas chromatography (GC) with direct injection sample introduction. This method requires testing...

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Detalles Bibliográficos
Autores principales: Poronsky, Christopher J., Cutrone, Jingfang Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790705/
https://www.ncbi.nlm.nih.gov/pubmed/29404048
http://dx.doi.org/10.1016/j.jpha.2017.03.009