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Degradation rates and products of fluticasone propionate in alkaline solutions

The apparent degradation rate constant of fluticasone propionate (FLT) in 0.1 M NaOH:methanol=1:1 at 37 °C was previously reported to be 0.169±0.003 h(−1), and four degradation products (products 1–4) were observed in the solution. The aims of the present study were to assess the degradation rates o...

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Detalles Bibliográficos
Autores principales: Tokumura, Tadakazu, Yoshida, Naoko, Mori-Yasumoto, Kanami, Shirota, Osamu, Kurita, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790711/
https://www.ncbi.nlm.nih.gov/pubmed/29404052
http://dx.doi.org/10.1016/j.jpha.2017.03.010