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Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles
Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to its low oral bioavailability, the loading of melatonin in polymeri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790749/ https://www.ncbi.nlm.nih.gov/pubmed/29404064 http://dx.doi.org/10.1016/j.jpha.2017.05.007 |