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Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles

Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to its low oral bioavailability, the loading of melatonin in polymeri...

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Detalles Bibliográficos
Autores principales:	Martins, Leiziani Gnatkowski, khalil, Najeh Maissar, Mainardes, Rubiana Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2017
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790749/ https://www.ncbi.nlm.nih.gov/pubmed/29404064 http://dx.doi.org/10.1016/j.jpha.2017.05.007

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