Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study

A simple, rapid and sensitive method based on an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an AC...

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Detalles Bibliográficos
Autores principales: Wang, Shixiao, Wang, Yang, Gao, Shuang, Zhang, Yuanyuan, Wang, Hanpei, Zhao, Longshan, Bi, Kaishun, Wang, Shaojie, Chen, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790751/
https://www.ncbi.nlm.nih.gov/pubmed/29404067
http://dx.doi.org/10.1016/j.jpha.2017.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790751/
https://www.ncbi.nlm.nih.gov/pubmed/29404067
http://dx.doi.org/10.1016/j.jpha.2017.07.004

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