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Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor

Brucella abortus induces an inflammatory response that stimulates the endocrine system resulting in the secretion of cortisol and dehydroepiandrosterone (DHEA). Osteoarticular brucellosis is the most common presentation of the active disease in humans, and we have previously demonstrated that B. abo...

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Detalles Bibliográficos
Autores principales: Gentilini, María Virginia, Pesce Viglietti, Ayelén Ivana, Arriola Benitez, Paula Constanza, Iglesias Molli, Andrea Elena, Cerrone, Gloria Edith, Giambartolomei, Guillermo Hernán, Delpino, María Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790783/
https://www.ncbi.nlm.nih.gov/pubmed/29434601
http://dx.doi.org/10.3389/fimmu.2018.00088