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N-Acetylmuramic Acid (MurNAc) Auxotrophy of the Oral Pathogen Tannerella forsythia: Characterization of a MurNAc Kinase and Analysis of Its Role in Cell Wall Metabolism

Tannerella forsythia is an anaerobic, Gram-negative oral pathogen that thrives in multispecies gingival biofilms associated with periodontitis. The bacterium is auxotrophic for the commonly essential bacterial cell wall sugar N-acetylmuramic acid (MurNAc) and, thus, strictly depends on an exogenous...

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Detalles Bibliográficos
Autores principales: Hottmann, Isabel, Mayer, Valentina M. T., Tomek, Markus B., Friedrich, Valentin, Calvert, Matthew B., Titz, Alexander, Schäffer, Christina, Mayer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790795/
https://www.ncbi.nlm.nih.gov/pubmed/29434575
http://dx.doi.org/10.3389/fmicb.2018.00019