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Comparative Evaluation of U.S. Brand and Generic Intravenous Sodium Ferric Gluconate Complex in Sucrose Injection: Biodistribution after Intravenous Dosing in Rats

Relative biodistribution of FDA-approved innovator and generic sodium ferric gluconate (SFG) drug products was investigated to identify differences in tissue distribution of iron after intravenous dosing to rats. Three equal cohorts of 42 male Sprague-Dawley rats were created with each cohort receiv...

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Detalles Bibliográficos
Autores principales: Beekman, Christopher R., Matta, Murali K., Thomas, Christopher D., Mohammad, Adil, Stewart, Sharron, Xu, Lin, Chockalingam, Ashok, Shea, Katherine, Sun, Dajun, Jiang, Wenlei, Patel, Vikram, Rouse, Rodney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791097/
https://www.ncbi.nlm.nih.gov/pubmed/29283393
http://dx.doi.org/10.3390/nano8010010