Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins

BACKGROUND: Cardiac fibrosis is a consequence of chronic chagasic cardiomyopathy (CCC). In other cardiovascular diseases, the protagonist role of fibroblasts in cardiac fibrosis is well established. However, the role of cardiac fibroblasts (CFs) in fibrosis during the CCC is not clear. Here, our aim...

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Detalles Bibliográficos
Autores principales: Coelho, Laura Lacerda, Pereira, Isabela Resende, Pereira, Mirian Claudia de Souza, Mesquita, Liliane, Lannes-Vieira, Joseli, Adesse, Daniel, Garzoni, Luciana Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791182/
https://www.ncbi.nlm.nih.gov/pubmed/29382361
http://dx.doi.org/10.1186/s13071-018-2614-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791182/
https://www.ncbi.nlm.nih.gov/pubmed/29382361
http://dx.doi.org/10.1186/s13071-018-2614-1

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