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Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate
BACKGROUND: The notochord has organizer properties and is required for floor plate induction and dorsoventral patterning of the neural tube. This activity has been attributed to sonic hedgehog (shh) signaling, which originates in the notochord, forms a gradient, and autoinduces shh expression in the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791209/ https://www.ncbi.nlm.nih.gov/pubmed/29423139 http://dx.doi.org/10.1186/s13227-017-0090-x |