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Imiquimod inhibits growth and induces differentiation of myeloid leukemia cell lines

BACKGROUND: The antitumoral effects of different Toll-like receptor (TLRs) agonists is mediated by activating immune responses to suppress tumors growth, although TLR ligands may also have a direct effect on tumoral cells. Given that TLR signaling induces hematopoietic cell differentiations this may...

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Detalles Bibliográficos
Autores principales: Villamón, Eva, González-Fernández, Javier, Such, Esperanza, Cervera, José Vicente, Gozalbo, Daniel, Luisa Gil, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791367/
https://www.ncbi.nlm.nih.gov/pubmed/29422777
http://dx.doi.org/10.1186/s12935-018-0515-1