Cargando…

Imiquimod inhibits growth and induces differentiation of myeloid leukemia cell lines

BACKGROUND: The antitumoral effects of different Toll-like receptor (TLRs) agonists is mediated by activating immune responses to suppress tumors growth, although TLR ligands may also have a direct effect on tumoral cells. Given that TLR signaling induces hematopoietic cell differentiations this may...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villamón, Eva, González-Fernández, Javier, Such, Esperanza, Cervera, José Vicente, Gozalbo, Daniel, Luisa Gil, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791367/ https://www.ncbi.nlm.nih.gov/pubmed/29422777 http://dx.doi.org/10.1186/s12935-018-0515-1

Ejemplares similares

Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities
por: de Blas, Elena, et al.
Publicado: (2016)

The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia
por: Shen, Qi, et al.
Publicado: (2012)

Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia
por: Cofre, Jaime, et al.
Publicado: (2012)

Acute myeloid leukemia and transcription factors: role of erythroid Krüppel-like factor (EKLF)
por: Ayala, Rosa, et al.
Publicado: (2012)

Anti-cancer effects of ginsenoside compound k on pediatric acute myeloid leukemia cells
por: Chen, Yan, et al.
Publicado: (2013)

DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia
por: Lu, Quanyi, et al.
Publicado: (2013)

CEBPG promotes acute myeloid leukemia progression by enhancing EIF4EBP1
por: Jiang, You, et al.
Publicado: (2021)

Risk factors affect accurate prognosis in ASXL1-mutated acute myeloid leukemia
por: Fan, Yi, et al.
Publicado: (2021)

MiR-99a may serve as a potential oncogene in pediatric myeloid leukemia
por: Zhang, Lidan, et al.
Publicado: (2013)

Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays
por: Yan-Fang, Tao, et al.
Publicado: (2012)

CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells
por: Wei, Xiao-Fang, et al.
Publicado: (2018)

Distinct associations of NEDD4L expression with genetic abnormalities and prognosis in acute myeloid leukemia
por: Chu, Ming-qiang, et al.
Publicado: (2021)

The prognosis biomarkers based on m6A-related lncRNAs for myeloid leukemia patients
por: Yang, Li-Rong, et al.
Publicado: (2022)

Treatment with G-CSF reduces acute myeloid leukemia blast viability in the presence of bone marrow stroma
por: Nomdedeu, Meritxell, et al.
Publicado: (2015)

High expression of miR-25 predicts favorable chemotherapy outcome in patients with acute myeloid leukemia
por: Niu, Mingshan, et al.
Publicado: (2019)

The assessment of minimal residual disease versus that of somatic mutations for predicting the outcome of acute myeloid leukemia patients
por: Salehzadeh, Serena, et al.
Publicado: (2019)

The mutual regulatory loop between TPTEP1 and miR-1303 in leukemogenesis of acute myeloid leukemia
por: Li, Li, et al.
Publicado: (2021)

Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human b lymphoma cell line bl36
por: Poirier, Florence, et al.
Publicado: (2001)

Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patients
por: Cao, Xin-xin, et al.
Publicado: (2018)

Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A
por: Uchino, Yoshihito, et al.
Publicado: (2015)

Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia
por: Gu, Siyu, et al.
Publicado: (2020)

Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation
por: Iriyama, Noriyoshi, et al.
Publicado: (2016)

Association between TERT gene polymorphisms and acute myeloid leukemia susceptibility in a Chinese population: a case–control study
por: Tong, Yong, et al.
Publicado: (2020)

Clinical and laboratory features of seven patients with acute myeloid leukemia (AML)-M2/M3 and elevated myeloblasts and abnormal promyelocytes
por: He, GanLin, et al.
Publicado: (2014)

Silencing long non-coding RNA HOTAIR exerts anti-oncogenic effect on human acute myeloid leukemia via demethylation of HOXA5 by inhibiting Dnmt3b
por: Wang, Si-Li, et al.
Publicado: (2019)

Identification of long non-coding RNA competing interactions and biological pathways associated with prognosis in pediatric and adolescent cytogenetically normal acute myeloid leukemia
por: Yin, Xuejiao, et al.
Publicado: (2018)

Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine
por: Tang, Li-juan, et al.
Publicado: (2019)

Complex Variant t(9;22) Chromosome Translocations in Five Cases of Chronic Myeloid Leukemia
por: Valencia, Ana, et al.
Publicado: (2009)

Establishment and characterization of HXWMF-1: the first mouse fibroblastic tumor cell line derived from leukemia-associated fibroblasts
por: Li, Yuanyuan, et al.
Publicado: (2021)

Differential effects of HIF-α isoforms on apoptosis in renal carcinoma cell lines
por: Doonachar, Alana, et al.
Publicado: (2015)

MLL2/KMT2D and MLL3/KMT2C expression correlates with disease progression and response to imatinib mesylate in chronic myeloid leukemia
por: Rabello, Doralina do Amaral, et al.
Publicado: (2018)

Long non-coding RNA NEAT1/miR-338-3p axis impedes the progression of acute myeloid leukemia via regulating CREBRF
por: Feng, Song, et al.
Publicado: (2020)

Characterization of a novel glucocorticoid-resistant human B-cell acute lymphoblastic leukemia cell line, with AMPK, mTOR and fatty acid synthesis pathway inhibition
por: Li, Yuanyuan, et al.
Publicado: (2021)

MHC class I-related chain A and B ligands are differentially expressed in human cervical cancer cell lines
por: del Toro-Arreola, Susana, et al.
Publicado: (2011)

Jacaric acid inhibits the growth of murine macrophage-like leukemia PU5-1.8 cells by inducing cell cycle arrest and apoptosis
por: Liu, Wai Nam, et al.
Publicado: (2015)

Protein kinase ERK contributes to differential responsiveness of human myeloma cell lines to IFNα
por: Song, Lun, et al.
Publicado: (2002)

HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line
por: Petrini, Marina, et al.
Publicado: (2013)

Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids
por: Valeria, Ponce de León, et al.
Publicado: (2005)

GSK-J4 induces cell cycle arrest and apoptosis via ER stress and the synergism between GSK-J4 and decitabine in acute myeloid leukemia KG-1a cells
por: Chu, Xuan, et al.
Publicado: (2020)

Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation
por: Sramek, Martin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0a3j2a6agcqujorobo3skiudcm