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Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

BACKGROUND: Autophagy plays a crucial role in chemotherapy resistance of triple-negative breast cancer (TNBC). Hence, autophagy-related gene 5 (ATG5), an essential molecule involved in autophagy regulation, is presumably associated with recurrence of TNBC. This study was aimed to investigate the pot...

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Detalles Bibliográficos
Autores principales: Li, Meiying, Ma, Fei, Wang, Jiayu, Li, Qing, Zhang, Pin, Yuan, Peng, Luo, Yang, Cai, Ruigang, Fan, Ying, Chen, Shanshan, Li, Qiao, Xu, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791378/
https://www.ncbi.nlm.nih.gov/pubmed/29382381
http://dx.doi.org/10.1186/s40880-018-0268-1