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O-Acetylation is essential for functional antibody generation against Staphylococcus aureus capsular polysaccharide

Staphylococcus aureus produces an antiphagocytic polysaccharide capsule to evade neutrophil-mediated killing. Many vaccines against encapsulated bacterial pathogens require generation of functional anti-capsular antibodies to mediate protection against infection and disease. Here it is shown that th...

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Detalles Bibliográficos
Autores principales: Scully, Ingrid L., Pavliak, Viliam, Timofeyeva, Yekaterina, Liu, Yongdong, Singer, Christine, Anderson, Annaliesa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791590/
https://www.ncbi.nlm.nih.gov/pubmed/29182428
http://dx.doi.org/10.1080/21645515.2017.1386360