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Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

To build comprehensive models of cellular states and interactions in normal and diseased tissue, genetic and proteomic information must be extracted with single-cell and spatial resolution. Here, we extended imaging mass cytometry to enable multiplexed detection of mRNA and proteins in tissues. Thre...

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Detalles Bibliográficos
Autores principales: Schulz, Daniel, Zanotelli, Vito Riccardo Tomaso, Fischer, Jana Raja, Schapiro, Denis, Engler, Stefanie, Lun, Xiao-Kang, Jackson, Hartland Warren, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791659/
https://www.ncbi.nlm.nih.gov/pubmed/29289569
http://dx.doi.org/10.1016/j.cels.2017.12.001