Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

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To build comprehensive models of cellular states and interactions in normal and diseased tissue, genetic and proteomic information must be extracted with single-cell and spatial resolution. Here, we extended imaging mass cytometry to enable multiplexed detection of mRNA and proteins in tissues. Thre...

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Detalles Bibliográficos
Autores principales: Schulz, Daniel, Zanotelli, Vito Riccardo Tomaso, Fischer, Jana Raja, Schapiro, Denis, Engler, Stefanie, Lun, Xiao-Kang, Jackson, Hartland Warren, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791659/
https://www.ncbi.nlm.nih.gov/pubmed/29289569
http://dx.doi.org/10.1016/j.cels.2017.12.001
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