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Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages

Specification of the three germ layers by graded Nodal signaling has long been seen as a paradigm for patterning through a single morphogen gradient. However, by exploiting the unique properties of the zebrafish embryo to capture the dynamics of signaling and cell fate allocation, we now demonstrate...

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Detalles Bibliográficos
Autores principales: van Boxtel, Antonius L., Economou, Andrew D., Heliot, Claire, Hill, Caroline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791662/
https://www.ncbi.nlm.nih.gov/pubmed/29275993
http://dx.doi.org/10.1016/j.devcel.2017.11.021