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Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages
Specification of the three germ layers by graded Nodal signaling has long been seen as a paradigm for patterning through a single morphogen gradient. However, by exploiting the unique properties of the zebrafish embryo to capture the dynamics of signaling and cell fate allocation, we now demonstrate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791662/ https://www.ncbi.nlm.nih.gov/pubmed/29275993 http://dx.doi.org/10.1016/j.devcel.2017.11.021 |