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Crack the state of silence: Tune the depth of cellular quiescence for cancer therapy
The regulation of cellular quiescence underlies numerous physiopathological phenomena. We recently found that quiescence depth can be tuned as to adjust a dimmer switch, by altering the expression of genes in the Retinoblastoma (Rb)-E2f pathway. Reducing quiescence depth may wake dormant cancer cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791855/ https://www.ncbi.nlm.nih.gov/pubmed/29404395 http://dx.doi.org/10.1080/23723556.2017.1403531 |