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T cell receptor repertoire among women who cleared and failed to clear cervical human papillomavirus infection: An exploratory proof-of-principle study

BACKGROUND: It is unknown why a minority of women fail to clear human papillomavirus (HPV) and develop precancer/cancer. Differences in T-cell receptor (TCR) repertoires may identify HPV16-infected women at highest-risk for progression to cancer. We conducted a proof-of-principle study nested within...

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Detalles Bibliográficos
Autores principales: Lang Kuhs, Krystle A., Lin, Shih-Wen, Hua, Xing, Schiffman, Mark, Burk, Robert D., Rodriguez, Ana Cecilia, Herrero, Rolando, Abnet, Christian C., Freedman, Neal D., Pinto, Ligia A., Hamm, David, Robins, Harlan, Hildesheim, Allan, Shi, Jianxin, Safaeian, Mahboobeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791954/
https://www.ncbi.nlm.nih.gov/pubmed/29385144
http://dx.doi.org/10.1371/journal.pone.0178167