Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating

The cellular PI3K/Akt and/or MEK/ERK signaling pathways mediate the entry process or endosomal acidification during infection of many viruses. However, their roles in the early infection events of group A rotaviruses (RVAs) have remained elusive. Here, we show that late-penetration (L-P) human DS-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Soliman, Mahmoud, Seo, Ja-Young, Kim, Deok-Song, Kim, Ji-Yun, Park, Jun-Gyu, Alfajaro, Mia Madel, Baek, Yeong-Bin, Cho, Eun-Hyo, Kwon, Joseph, Choi, Jong-Soon, Kang, Mun-Il, Park, Sang-Ik, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792019/
https://www.ncbi.nlm.nih.gov/pubmed/29352319
http://dx.doi.org/10.1371/journal.ppat.1006820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792019/
https://www.ncbi.nlm.nih.gov/pubmed/29352319
http://dx.doi.org/10.1371/journal.ppat.1006820

Ejemplares similares