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A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment
Targeting key regulators of the cancer stem cell phenotype to overcome their critical influence on tumor growth is a promising new strategy for cancer treatment. Here we present a modeling framework that operates at both the cellular and molecular levels, for investigating IL-6 mediated, cancer stem...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792033/ https://www.ncbi.nlm.nih.gov/pubmed/29351275 http://dx.doi.org/10.1371/journal.pcbi.1005920 |