Endothelial cells express NKG2D ligands and desensitize antitumor NK responses

Natural Killer (NK) cells confer protection from tumors and infections by releasing cytotoxic granules and pro-inflammatory cytokines upon recognition of diseased cells. The responsiveness of NK cells to acute stimulation is dynamically tuned by steady-state receptor-ligand interactions of an NK cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Thornton W, Kim, Alexander Byungsuk, Li, P Jonathan, Wang, Jiaxi, Jackson, Benjamin T, Huang, Kristen Ting Hui, Zhang, Lily, Raulet, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792093/
https://www.ncbi.nlm.nih.gov/pubmed/29231815
http://dx.doi.org/10.7554/eLife.30881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792093/
https://www.ncbi.nlm.nih.gov/pubmed/29231815
http://dx.doi.org/10.7554/eLife.30881

Ejemplares similares