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Endothelial cells express NKG2D ligands and desensitize antitumor NK responses

Natural Killer (NK) cells confer protection from tumors and infections by releasing cytotoxic granules and pro-inflammatory cytokines upon recognition of diseased cells. The responsiveness of NK cells to acute stimulation is dynamically tuned by steady-state receptor-ligand interactions of an NK cel...

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Detalles Bibliográficos
Autores principales:	Thompson, Thornton W, Kim, Alexander Byungsuk, Li, P Jonathan, Wang, Jiaxi, Jackson, Benjamin T, Huang, Kristen Ting Hui, Zhang, Lily, Raulet, David H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792093/ https://www.ncbi.nlm.nih.gov/pubmed/29231815 http://dx.doi.org/10.7554/eLife.30881

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