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Does adaptation to vertebrate codon usage relate to flavivirus emergence potential?

Codon adaptation index (CAI) is a measure of synonymous codon usage biases given a usage reference. Through mutation, selection, and drift, viruses can optimize their replication efficiency and produce more offspring, which could increase the chance of secondary transmission. To evaluate how higher...

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Detalles Bibliográficos
Autores principales: Di Paola, Nicholas, Freire, Caio César de Melo, Zanotto, Paolo Marinho de Andrade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792106/
https://www.ncbi.nlm.nih.gov/pubmed/29385205
http://dx.doi.org/10.1371/journal.pone.0191652