DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies remains scarce. Therefore, we evaluated whether DNAm in whole blood mediated the ass...

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Detalles Bibliográficos
Autores principales: Tobi, Elmar W., Slieker, Roderick C., Luijk, René, Dekkers, Koen F., Stein, Aryeh D., Xu, Kate M., Slagboom, P. Eline, van Zwet, Erik W., Lumey, L. H., Heijmans, Bastiaan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792223/
https://www.ncbi.nlm.nih.gov/pubmed/29399631
http://dx.doi.org/10.1126/sciadv.aao4364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792223/
https://www.ncbi.nlm.nih.gov/pubmed/29399631
http://dx.doi.org/10.1126/sciadv.aao4364

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