WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

Loss-of-function mutations and deletions in Wilms tumor 1 (WT1) gene are present in approximately 10% of T-cell acute lymphoblastic leukemia. Clinically, WT1 mutations are enriched in relapsed series and are associated to inferior relapse-free survival in thymic T-cell acute lymphoblastic leukemia c...

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Detalles Bibliográficos
Autores principales: Bordin, Fulvio, Piovan, Erich, Masiero, Elena, Ambesi-Impiombato, Alberto, Minuzzo, Sonia, Bertorelle, Roberta, Sacchetto, Valeria, Pilotto, Giorgia, Basso, Giuseppe, Zanovello, Paola, Amadori, Alberto, Tosello, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792271/
https://www.ncbi.nlm.nih.gov/pubmed/29170254
http://dx.doi.org/10.3324/haematol.2017.170431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792271/
https://www.ncbi.nlm.nih.gov/pubmed/29170254
http://dx.doi.org/10.3324/haematol.2017.170431

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