Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia

Felty syndrome is a rare disease defined by neutropenia, splenomegaly, and rheumatoid arthritis. Sometimes the differential diagnosis between Felty syndrome and large granular lymphocyte leukemia is problematic. Recently, somatic STAT3 and STAT5B mutations were discovered in 30–40% of patients with...

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Detalles Bibliográficos
Autores principales: Savola, Paula, Brück, Oscar, Olson, Thomas, Kelkka, Tiina, Kauppi, Markku J., Kovanen, Panu E., Kytölä, Soili, Sokka-Isler, Tuulikki, Loughran, Thomas P., Leirisalo-Repo, Marjatta, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792275/
https://www.ncbi.nlm.nih.gov/pubmed/29217783
http://dx.doi.org/10.3324/haematol.2017.175729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792275/
https://www.ncbi.nlm.nih.gov/pubmed/29217783
http://dx.doi.org/10.3324/haematol.2017.175729

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