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Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia
Felty syndrome is a rare disease defined by neutropenia, splenomegaly, and rheumatoid arthritis. Sometimes the differential diagnosis between Felty syndrome and large granular lymphocyte leukemia is problematic. Recently, somatic STAT3 and STAT5B mutations were discovered in 30–40% of patients with...
Autores principales: | Savola, Paula, Brück, Oscar, Olson, Thomas, Kelkka, Tiina, Kauppi, Markku J., Kovanen, Panu E., Kytölä, Soili, Sokka-Isler, Tuulikki, Loughran, Thomas P., Leirisalo-Repo, Marjatta, Mustjoki, Satu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792275/ https://www.ncbi.nlm.nih.gov/pubmed/29217783 http://dx.doi.org/10.3324/haematol.2017.175729 |
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