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PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly
Mutations in proline-rich transmembrane protein 2 (PRRT2) are associated with a range of paroxysmal neurological disorders. PRRT2 predominantly localizes to the pre-synaptic terminals and is believed to regulate neurotransmitter release. However, the mechanism of action is unclear. Here, we use reco...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792450/ https://www.ncbi.nlm.nih.gov/pubmed/29346777 http://dx.doi.org/10.1016/j.celrep.2017.12.056 |