The effect of PU.1 knockdown on gene expression and function of mast cells

PU.1 is a hematopoietic cell-specific transcription factor. In the current study, we investigated the role of PU.1 in the gene expression and the function of mouse mast cells (MCs) in vitro and in vivo. When PU.1 siRNA was introduced into bone marrow-derived MCs (BMMCs), IgE-mediated activation was...

Descripción completa

Detalles Bibliográficos
Autores principales: Oda, Yoshihito, Kasakura, Kazumi, Fujigaki, Izumi, Kageyama, Azusa, Okumura, Ko, Ogawa, Hideoki, Yashiro, Takuya, Nishiyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792452/
https://www.ncbi.nlm.nih.gov/pubmed/29386516
http://dx.doi.org/10.1038/s41598-018-19378-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792452/
https://www.ncbi.nlm.nih.gov/pubmed/29386516
http://dx.doi.org/10.1038/s41598-018-19378-y

Ejemplares similares