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Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase

The membrane-associated, processive and retaining glycosyltransferase PglH from Campylobacter jejuni is part of the biosynthetic pathway of the lipid-linked oligosaccharide (LLO) that serves as the glycan donor in bacterial protein N-glycosylation. Using an unknown counting mechanism, PglH catalyzes...

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Detalles Bibliográficos
Autores principales: Ramírez, Ana S., Boilevin, Jérémy, Mehdipour, Ahmad Reza, Hummer, Gerhard, Darbre, Tamis, Reymond, Jean-Louis, Locher, Kaspar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792488/
https://www.ncbi.nlm.nih.gov/pubmed/29386647
http://dx.doi.org/10.1038/s41467-018-02880-2